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Family history, age increase risk of skin cancer.(Clinical Rounds)

OB GYN News

| August 01, 2005 | Sullivan, Michele G. | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

ST. LOUIS -- Family history is a strong risk factor for melanoma in women, while age appears to be the biggest risk for the development of basal cell carcinoma, Abrar Qureshi, M.D., said at the annual meeting of the Society for Investigative Dermatology.

Dr. Qureshi of Harvard University, Boston, used data from the ongoing Nurses' Health Study to examine independent risk factors for melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC). His study examined incident cases of skin cancer among 113,333 women who were followed from 1984 to 2000.

BCC was the most common cancer in the group, with 7,854 cases. There were 870 cases of SCC and 370 cases of melanoma.

Based on a preliminary analysis of the data, he concluded that age was the biggest risk factor for BCC. Looking at age-specific incidence rates, between ages 55-59 years, the incidence rate was about 700 cases per 100,000 person-years, but after age 65, the rate rose to above 2,000. "You can see, it's quite different above age 65," Dr. Qureshi said.

The incidence rate for melanoma was 44 cases per 100,000 person-years, and the rate of SCC was 104 cases per 100,000 person-years. Age did ...

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