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Lower [beta]-HCG threshold for pregnancies of unknown location?(Obstetrics)
COPENHAGEN -- Roughly 20% of pregnancies currently regarded as failing intrauterine pregnancies may actually be viable, results of a prospective, observational study suggest.
Serum HCG guidelines for recognizing intrauterine pregnancy viability should be revised to reflect this information, Emma Kirk, M.D., said at the annual meeting of the European Society of Human Reproduction and Embryology.
Evidence suggests that about one-third of pregnancies of unknown location (PUL) are actually intrauterine pregnancies that are too small to visualize on transvaginal ultrasound. Guidelines issued by the American Society for Reproductive Medicine advise that in such cases a suboptimal rise in the [beta]-HCG level--defined as a rise of less than 66% over 48 hours or an HCG ratio (HCG at 48 hours to HCG at 0 hours) of less than 1.66--is predictive of nonviability, Dr. Kirk said.
In many cases, such HCG findings would prompt an intervention, such as laparoscopy, to look for a possible ectopic pregnancy, but clinicians ...
- Research in the area of transvaginal ultrasound reported from University of...
- Magazine article from: Women's Health Weekly October 30, 2008 700+ words
...determine whether hCG ratio at 48 h can...viability of intrauterine pregnancies of uncertain...offs for the hCG ratio need to be...Reproduction (The hCG ratio can predict...viability of the intrauterine pregnancies of uncertain...
- Start with US to diagnose ectopic pregnancy.(OBSTETRICS)
- Magazine article from: OB GYN News Boschert, Sherry September 1, 2009 700+ words
...with the fewest interrupted intrauterine pregnancies (less than 1%). Some other...ultrasounds will show evidence of intrauterine pregnancies even when the beta-hCG results...ultrasound can identify 33% of normal intrauterine pregnancies, 28% of spontaneous miscarriages...
- Higher VEGF levels tied to ectopic pregnancy. (Vascular Endothelial Growth...
- Magazine article from: OB GYN News Johnson, Kate December 15, 2001 700+ words
...compared with those with arrested intrauterine pregnancies, Dr. Togas Tulandi reported...306.1 pg/mL), arrested intrauterine pregnancies (69.7 pg/mL), and normal intrauterine pregnancies (27 pg/mL). "This could...
- Color Flow Doppler Guides Ectopic Management.
- Magazine article from: OB GYN News BOSCHERT, SHERRY July 1, 2001 700+ words
...flow--exhibited by normal intrauterine pregnancies and some abnormal intrauterine pregnancies that will later miscarry...approximately 15% of normal intrauterine pregnancies, however, and the measurement...
- Anxious Patients Often Want Very Early Ultrasound Exam.
- Magazine article from: OB GYN News BOSCHERT, SHERRY June 15, 2001 700+ words
...5 and 5 weeks' gestation in intrauterine pregnancies, real-time ultrasound or color...marker, which is found only in intrauterine pregnancies, is used to rule out ectopic...yolk sac can be seen in 50% of intrauterine pregnancies at 5 weeks' gestation, in 95...
- Research from University of Sydney in the area of ectopic pregnancy published.
- Magazine article from: Women's Health Weekly September 24, 2009 700+ words
...48 h, indicating the trophoblast is still active, should be targeted for methotrexate. By calculating the pre-treatment hCG ratio (hCG 48 h/hCG 0 h), it is possible to triage women with an ectopic pregnancy for conservative management. There are...
- Researchers' work from University of Sydney focuses on ectopic pregnancy.
- Magazine article from: Women's Health Weekly August 13, 2009 700+ words
...level of the uterine fundus and/or in Morison's pouch (hepatorenal space). Subsequent management was based upon the hCG ratio at 48 h. All the women were managed as inpatients until the abdominal pain settled and the serum hCG levels were falling...
- ABORTION AND THE PILL.
- Magazine article from: Catholic Insight Shea, J. B. October 1, 2000 700+ words
...ratio of ectopic (tubal) pregnancies to intrauterine pregnancies in women using OCs: If it were true that...significantly more ectopic pregnancies, relative to intrauterine pregnancies, occur in women who use OCs [7-11...
