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Ertapenem found effective for intraabdominal infections.(Gynecology)
MIAMI -- A daily dose of intravenous ertapenem for intraabdominal infections proved as effective as piperacillin/tazobactam administered every 6 hours, Nicholas Namias, M.D., said in a poster presented at the joint annual meeting of the Surgical Infection Society and the Surgical Infection Society-Europe.
The randomized, double-blind study included 494 men and women aged at least 18 years who had systemic inflammatory responses and physical findings suggestive of intraabdominal infections resulting from surgical interventions such as open laparotomy, laparoscopic surgery, and percutaneous drainage.
A total of 247 received 1 gram of intravenous ertapenem per day and 247 received 3.375 g of intravenous piperacillin/tazobactam every 6 hours for 4-14 days, wrote Dr. Namias, of the University of Miami, and his colleagues.
Response rates were similar. A total of 122 ertapenem patients and 107 piperacillin/tazobactam patients were microbiologically evaluable at 2 weeks, and favorable clinical responses were shown in 82.1% and ...
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...Kamal Itani, M.D., and associates in a poster presented at the joint annual meeting of the Surgical Infection Society and the Surgical Infection Society-Europe. "We expected linezolid to be better, but it was even better than we expected...