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Cortisol dips in PCOS patients treated for sleep apnea: study.(Gynecology)

OB GYN News

| October 01, 2005 | Bates, Betsy | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SAN DIEGO -- A small study has found that treating obstructive sleep apnea in patients with polycystic ovary syndrome lowered their cortisol levels at night as well as during the daytime.

Obstructive sleep apnea symptoms also greatly improved in five nondiabetic PCOS patients who received continuous positive airway pressure (CPAP) for 8 weeks as part of a study presented at the annual meeting of the Endocrine Society.

Previous research has determined that the risk of obstructive sleep apnea is 30-fold to 40-fold higher in women with PCOS compared with weight-matched controls. It has been theorized that there may be a link between obstructive sleep apnea and the metabolic and hormonal abnormalities associated with the disease.

"These findings strongly suggest that obstructive sleep apnea is likely to contribute to elevated cortisol levels in women with PCOS and could play a role in the risk for adverse metabolic alterations in this patient population," concluded researchers Eve Van Cauter, Ph.D., and Esra Tasali, M.D., of the department of medicine at the University of Chicago, who presented a poster at the meeting.

Subjects in the study were in their early to mid-30s and had a ...

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