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Arterial aging signs seen in young PCOS patients.(Gynecology)
SAN DIEGO -- Young women with polycystic ovary syndrome have evidence of endothelial dysfunction and low-grade, chronic inflammatory markers characteristic of much older patients, researchers reported at the annual meeting of the Endocrine Society.
Evanthia Diamanti-Kandarakis, M.D., and associates at Laiko Hospital of the University of Athens compared endothelial function and inflammatory cytokines in 25 women with PCOS and 20 age-matched controls with similar body mass index (BMI) measurements and waist-hip ratios. The women were in their mid to late 20s and had BMIs of about 26-29 kg/[m.sup.2].
Endothelial function was determined by flow-mediated dilatation of the brachial artery on ultrasound, plus endothelin-1 (ET-1) plasma levels. Numerous cytokines were measured in blood to assess arterial inflammation.
Subjects with PCOS had significantly lower percentages of flow-mediated dilatation than controls (3.47% vs. 9.26%). Nitrate-induced dilatation, measured to exclude smooth muscle cell injury, was not significantly different in the two groups. Significantly higher levels of ET-1, intracellular adhesion ...
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- Magazine article from: Women's Health Weekly May 27, 2004 700+ words
...cross-sectional study of 116 PCOS patients and 94 controls matched for body...indicator of CVD - are increased in PCOS patients. The researchers measured two...Tests indicated that 36.8% of PCOS patients had extremely high (above 5 mg...
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- Magazine article from: Women's Health Weekly June 3, 2004 700+ words
...cross-sectional study on 116 PCOS patients and 94 BMI (body mass index...indicator of CVD - are increased in PCOS patients. The researchers measured two...Tests indicated that 36.8% of PCOS patients had extremely high (above 5 mg...
- Increased Risk of Cardiovascular Disease Shown in PCOS Patients.
- Press release article from: PR Newswire May 5, 2004 700+ words
...cross-sectional study on 116 PCOS patients and 94 BMI-matched controls...indicator of CVD -- are increased in PCOS patients. The researchers measured two...indicated that 36.8 percent of PCOS patients had extremely high (above 5 mg...
- Body-fat distribution compared between PCOS patients and type 2 diabetics.
- Newspaper article from: Obesity, Fitness & Wellness Week December 4, 2004 700+ words
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- Screen PCOS patients' sisters, mothers for diabetes. (Higher Androgen Levels,...
- Magazine article from: OB GYN News Kirn, Timothy F. September 15, 2002 700+ words
...that about half of the sisters of PCOS patients who actually have polycystic ovaries...ultrasound to determine whether 134 PCOS patients had polycystic ovaries. They then...insulin levels of the sisters with PCOS with those of sisters who did not...
- Test All PCOS Patients For Thyroid Disease.(Brief Article)
- Magazine article from: Family Practice News JANCIN, BRUCE October 1, 2001 700+ words
...controls and in 43% (25) of PCOS patients; 20 of these 25 also had an abnormal...hypoechogenicity. In addition, 17% of the PCOS group had clinical autoimmune thyroiditis...however, were normal in all PCOS patients and controls. Women are known...
- Metformin May Be Useful For PCOS Patients With Metabolic Syndrome...
- Magazine article from: Women's Health Weekly August 9, 2001 700+ words
...endocrine and menstrual function in PCOS and thus it comes as no surprise...fertility problems experienced by PCOS patients, the drug may aid weight loss...suggest that it may be beneficial for PCOS patients with features of the metabolic...