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Oral mucositis drug approved for use in some Ca.(Dermatologic Therapy)

Publication: Skin & Allergy News

Publication Date: 01-FEB-05

Author: Evans, Jeff
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COPYRIGHT 2005 International Medical News Group

The Food and Drug Administration has approved the recombinant human keratinocyte growth factor palifermin as the only drug indicated to reduce the incidence and duration of severe oral mucositis in patients with hematologic cancers who require hematopoietic stem cell transplantation after chemoradiotherapy.

Prior to palifermin, clinicians could offer only analgesics to reduce the severe pain that accompanies oral mucositis and antibiotics to reduce the risk of systemic infection.

The limited indication given so far to palifermin could widen in the future to include other indications, based on the results of upcoming studies of palifermin in...

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