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Extra vitamin D cuts fall risk in elderly women, not men.(Gynecology)

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| April 15, 2006 | Johnson, Kate | COPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Elderly women, particularly those who are less active, can significantly reduce their risk of falling by taking a daily supplement of vitamin D, according to a new study. However, the supplement does not protect men in the same age group.

Daily supplementation with 700 IU of cholecalciferol and 500 mg of calcium citrate malate reduced the odds of falling by 46% in ambulatory older women and by 65% in less active women, noted Dr. Heike A. Bischoff-Ferrari of University Hospital Zurich, and colleagues.

The supplementation is not only "very inexpensive, well tolerated, and simple" but also has similar or greater benefit than more expensive and time-intensive interventions, added the authors (Arch. Intern. Med. 2006;166:424-30).

The findings are from a secondary analysis of a 3-year double-blind placebo-controlled study that looked at the effect of cholecalciferol-calcium on bone mineral density. Primary results of the study noted a 60% reduction of osteoporotic fractures with the supplement, compared with placebo. The secondary analysis examined the risk of falling during the study period for 199 men and 246 women aged 65 years or older.

Multivariate analysis controlled for age, gender, baseline body mass index, dietary calcium, baseline plasma 25-hydroxyvitamin D (25-OHD) levels, baseline plasma intact parathyroid hormone levels, activity level, baseline smoking status, baseline alcohol use, baseline comorbid conditions, baseline creatinine clearance and length of follow-up.

Overall, cholecalciferol-calcium supplementation did not significantly reduce the risk of falling compared with placebo, with 49% of men and 55% of women reporting at least one fall during the study period. However, multivariate analysis revealed ...

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Source: HighBeam Research, Extra vitamin D cuts fall risk in elderly women, not men.(Gynecology)

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