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MIAMI BEACH -- Continuous subcutaneous insulin lispro infusion appears to be superior to multiple daily insulin lispro injections for the treatment of pregnant women with type 1 diabetes, Dr. Giorgio Mello reported at the annual meeting of the Society for Maternal-Fetal Medicine.
In a randomized controlled study of 71 pregnant women with type 1 diabetes and 142 matched, nondiabetic, pregnant controls, continuous subcutaneous insulin infusions (CSII) were found to mimic more closely than multiple daily injections (given as a premeal bolus) the normal postprandial glucose excursion pattern.
The CSII approach also was associated with fetal fat mass growth patterns similar to those seen in normal pregnancies, said Dr. Mello of the University of Florence, Italy.
The postprandial glucose excursions ...
Source: HighBeam Research, Continuous insulin infusion rated superior.(Obstetrics)