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MIAMI BEACH -- Intraumbilical vein injection with oxytocin following cord clamp was effective for preventing placental retention and reducing postpartum blood loss in a randomized, placebo-controlled, double-blind study presented at the annual meeting of the Society for Maternal-Fetal Medicine.
A number of studies have shown oxytocin to be of benefit for reducing the need for manual removal of the placenta and for reducing risk of postpartum hemorrhage in patients with a retained placenta, but this study is the first to suggest that, although oxytocin does not reduce the duration of the third stage of labor, it may be beneficial in preventing its complications, Dr. Labib M. Ghulmiyyah said.
A total of 79 women with uncomplicated singleton pregnancies were randomized to receive 30 mL of saline or 20 U of oxytocin in 30 mL of saline. The mean time to placental delivery did not differ significantly between the two groups (7.8 minutes in the saline group vs. 5.9 minutes in the oxytocin group), but significantly more women in the saline group than in the oxytocin group had a retained placenta after 15 minutes (5 vs. 0 women).
Furthermore, the groups had similar mean hemoglobin levels prior to delivery ...