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Expert lists bone turnover markers' pros, cons.(Brief article)
SAN DIEGO -- A chief advantage of assessing bone turnover markers such as serum osteocalcin and urine hydro-xyproline in osteoporosis patients is their integrated assessment of skeletal metabolism, Dr. Marc C. Hochberg said at the annual meeting of the International Society for Clinical Densitometry.
Other advantages are they show rapid, large changes with therapy; automated assays are widely available, and they're less expensive than dual-energy x-ray absorptiometry, although more expensive than ultrasound; and elevated turnover is associated with fracture risk, independent of bone mineral density.
"As with everything, there are ...
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