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The effects of hypercapnia, supplemental oxygen, and dexamethasone on surgical wound infection.(CLINICAL TRIAL REVIEW)
This study is currently recruiting patients. Verified and sponsored by Outcomes Research Group. We will test the hypotheses that mild hypercapnia and supplemental oxygen reduce wound infection risk in patients undergoing colon resection. We will simultaneously test the hypothesis that low-dose dexamethasone (a common treatment for postoperative nausea and vomiting) does not increase infection risk.
Condition Intervention
Phase Surgical Behavior: Mild intraoperative hypercapnia Phase III Wound (50 mmHg vs. 30 mmHg) Infection Behavior: Supplemental oxygen Surgery, (80% vs. 30%) Colon Drug: 4 mg dexamethasone vs. ...
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