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Gait problems may be linked with dementia.

UPI NewsTrack

| January 24, 2006 | COPYRIGHT 2004 United Press International. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

CHICAGO, Jan. 24 (UPI) -- A study at Chicago's Rush University Medical Center suggests gait problems often progressive in old age are related to risk of dementia and death.

The study found neurofibrillary tangles in the substantia nigra -- a part of the brain that is subject to cell loss in Parkinson's disease -- are associated with gait impairment in older people with and without dementia. The more tangle pathology in the substantia nigra, the more impaired the person's gait was before death.

The study involved 86 autopsied older subjects. Although fewer than half had dementia, nearly 78 percent had neurofibrillary tangles in the substantia…

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