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SAN DIEGO -- Certain pregnancy complications appear to be strongly associated with stroke later in life, offering a golden opportunity for early education and prevention efforts, according to a study presented at the annual meeting of the American Neurological Association. Dr. Monique V. Chireau and her associates at Duke University School of Medicine and the Durham (N.C.) VA Medical Center, utilized the university's Perinatal and Health Services outcomes database to elicit information about more than 40,000 women who gave birth between 1979 and 2005.
They then did a look-back analysis to compare the pregnancies of 162 women who later had strokes with 306 well-matched controls who delivered at about the same time but had no record of stroke in subsequent years of the study.
Women who had strokes were 70% more likely than matched controls to have had a pregnancy complication, defined as abruption, preeclampsia, preterm birth, gestational diabetes, in utero fetal demise, small-for-gestational age, large-for-gestational age, oligohydramnios, postpartum hemorrhage, and stillbirth.
Analyzed individually, the complications most strongly associated with ...