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Recurrent miscarriage tied to insulin resistance: Check fasting insulin levels.

OB GYN News

| January 15, 2002 | Johnson, Kate | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

ORLANDO, FLA. -- Women who have had at least two miscarriages are more than twice as likely to have insulin resistance as those without recurrent pregnancy loss, according to results of a study of 172 women.

"The women in my study had normal fasting glucose levels, and that's what most physicians use to test for diabetes. But if you looked at their fasting insulin, it was greatly elevated in those who had insulin resistance. So you need to test both," Dr. LaTasha Barker said in an interview during the annual meeting of the American Society for Reproductive Medicine.

Insulin resistance is commonly found in women with polycystic ovarian syndrome (PCOS) and has been associated with the classic PCOS characteristics, including obesity, hirsutism, anovulation, and infertility. In Dr. Barker's study, which was presented in poster form at the meeting, more than half of the women with insulin resistance had no signs or symptoms of the disorder other than RPL.

"About 60% of patients didn't fit the classical picture, so regardless of how they look, everyone should be tested for insulin resistance if they have recurrent pregnancy loss," said Dr. Barker, a senior resident at the University of Tennessee Health Science Center, Memphis.

The study included 74 ...

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