AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Do third-generation OCs carry a higher risk of venous thrombosis than second-generation OCs? (PRO & CON).
[YES]
We systematically put together all the evidence that is available in our metaanalysis (BMJ 323[7305]:131-37, 2001). From that analysis you can clearly see that there is an excess risk when you use third-generation oral contraceptives, no matter which way you look at it, and it is consistent.
The overall adjusted odds ratio for third- vs. second-generation OCs was 1.7; among first-time users the odds ratio was 3.3.
Based on these data, women who are first-time users are recommended to start with a second-generation 0C. With regard to women who are already using a third-generation pill, at the time they are renewing the prescription they should be asked what their experience has been with a second-generation pill.
Growth of hair on the face, differences with acne, headaches, tenderness in the breast, these are all side effects of OCs that are very personal to the woman. There are actually no good studies comparing side effects. But some women have very strong opinions that should be heard.
Physicians should take that information into consideration in suggesting that women switch back. They should talk to patients about the fact that there is not a very high risk of venous thrombosis (VT), but that it is an avoidable risk.
We are not saying that all women who are taking third-generation OCs now should go off them. We are trying to provide some balance in addressing these issues; the women should be counseled.
- Third-generation OCs safe, health officials say.
- Magazine article from: Contraceptive Technology Update December 1, 1999 700+ words
...says Mellemkjaer. Among women, the admission rates...mortality rates for either women or men. The finding...thromboembolism among women supports the hypothesis that third-generation OCs increase the risk of...look at the individual woman admitted with venous...
- Third-generation OCs don't increase VTE risk.
- Magazine article from: Contraceptive Technology Update November 1, 2000 700+ words
...clots in British women in the three years...when use of third-generation OCs fell from 54% to 14% in women ages 15 to 49 who...the use of third-generation OCs fell during the period...venous clots among women taking the pill did...
- Oral Contraceptives and the Risk of Myocardial Infarction.
- Magazine article from: Internal Medicine Alert April 29, 2002 700+ words
...first- and second-generation OCs. Source: Tanis...RATIO enrolled women aged 18-49 years...3) for third-generation OCs. The amount of estrogen...Tanis et al compared women who used second-generation OCs with levonorgestrel...
- International Study of Oral Contraceptives Shows No Difference in Risk of...
- Press release article from: PR Newswire October 20, 1997 700+ words
...A second study of 817 showed that women taking second generation OCs were at nearly three times the risk...infarction in those taking third generation OCs, compared to women taking second generation OCs. Dr. Michael Lewis, of Potsdam...
- Oral contraceptives: warning on certain brands. (Desogen, Ortho-Cept and others)
- Newspaper article from: HealthFacts December 1, 1995 700+ words
...these third-generation OCs was conducted...stated that women taking a brand...Medicine advised women to complete...of third-generation OCs would be offset...of third-generation OCs. ACOG does...recommend that women change their...
- No link between OC use and heart attack.
- Magazine article from: Contraceptive Technology Update October 1, 1999 700+ words
...heart attack) in women who use oral contraceptives...second- and third-generation OCs when it comes to...comparing use of third-generation OCs with use of second-generation OCs. Researchers involved...found that of those women under age 45 who...
- No link between OC use and heart attack.(oral contraceptives)(Brief Article)
- Magazine article from: Contraceptive Technology Update October 1, 1999 700+ words
...heart attack) in women who use oral contraceptives...second-and third-generation OCs when it comes to...comparing use of third-generation OCs with use of second-generation OCs. Researchers involved...found that of those women under age 45 who...
- Public Citizen calls for US FDA to ban third-gen oral contraceptives.(United...
- Newspaper article from: Pharma Marketletter February 12, 2007 700+ words
...estimated that American women filled more than 7...prescriptions for third-generation OCs from November 2005 to...could save hundreds of women a year from developing...the dangers of third-generation OCs. This effort includes...on YouTube in which women explain why safe ...
