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John Ioannidis, M.D., "Contradicted and Initially Stronger Effects in Highly Cited Clinical Research," Journal of the American Medical Association, July 13, 2005 (jama.ama-assn.org)
Science progresses in steps. Experimentation leads to publication of results in scientific journals, which ensure quality control by means of peer review. Publication is only the first step, however, as the most important question in science is whether others can reproduce the results. There have been suggestions that too much weight is currently placed on publication, and that not enough work is being done to test published findings. This is especially important when public policy is based on scientific results.
Medical science, because of the life and death issues involved, is one scientific area where testing and ...
Source: HighBeam Research, Science is fallible, too.(SCIENCE AND THE ENVIRONMENT)(Contradicted...