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Life-threatening reactions reported with anticonvulsant lamotrigine. (Also Confused With Other Drugs).

Publication: Skin & Allergy News

Publication Date: 01-JAN-02

Author: Boschert, Sherry
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COPYRIGHT 2002 International Medical News Group

LAS VEGAS - One in every 100 children and 3 in every 1,000 adults given the anticonvulsant lamotrigine will develop life-threatening cutaneous eruptions, according to Dr. Adelaide A. Hebert.

Ten percent of all patients on lamotrigine will develop erythema and a maculopapular rash, usually within the first 2-8 weeks of therapy. One percent will develop Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, and/or pruritus.

Alert your staff about this problem so that they promptly report any patient on lamotrigine (Lamictal) who complains of fever, rash,...

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