AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Contradicts long-held belief: mouse study: oocyte and follicle renewal ongoing.(Gynecology)
A new study in mice raises the possibility that oocyte and follicle renewal are still ongoing in the postnatal ovary, contradicting a central tenet of reproductive biology that most mammalian females are born with a finite, nonrenewing pool of germ cells enclosed within follicles.
"This is very promising work," said Dr. Marian Damewood, president of the American Society for Reproductive Medicine. "The study is in mice, so it's not clear if this can be replicated in the human female. But if it can, it would be one of the biggest breakthroughs since in vitro fertilization more than 25 years ago."
She cautioned that the results have to be confirmed, and that researchers must still determine the mechanisms that sustain germ cells and assess the relative use of follicles generated during fetal life, compared with those produced by adult germ cells.
The current study established the existence of proliferative germ cells that sustain oocyte and follicle production in the postnatal mammalian ovary, reported Joshua Johnson, Ph.D., and his colleagues at Harvard Medical School, Boston.
The ...
- NIH-funded researchers transform embryonic stem cells into human germ cells.
- Newspaper article from: NewsRx Science November 15, 2009 700+ words
...transform human embryonic stem cells into germ cells, the embryonic cells that ultimately...will allow researchers to observe human germ cells-previously inaccessible-in laboratory...study. "Laboratory observation of human germ cells has the potential to yield important...
- Mouse Embryonic Germ Cells, Male Gametes Created in the Lab; Findings Have...
- News wire article from: Ascribe Higher Education News Service December 10, 2003 700+ words
...created a continuously growing line of embryonic germ cells - primitive cells in the embryo that mature to...online edition of the journal Nature. EMBRYONIC GERM CELLS Embryonic germ cells are a unique group of cells that the embryo sets...
- Germ Cells and the Germ Cell Line
- Encyclopedia entry from: The Gale Encyclopedia of Science January 1, 2008 700+ words
Germ Cells and the Germ Cell Line Germ cells are one of two fundamental cell types in the human body. Germ cells are responsible for the production of sex cells or gametes (in humans, ovum and spermatozoa). Germ cells also constitute a cell...
- Male germ cells function as spermatogonial stem cells producing functional...
- Magazine article from: Stem Cell Week June 28, 2004 700+ words
...com & NewsRx.net) -- Male germ cells function as spermatogonial stem cells...cells that originate from primordial germ cells (PGCs) in the early embryo. Although...it is not clear whether fetal male germ cells function as spermatogonial stem cells...
- Chemical guides germ cells to gonads. (Putting Out the Welcome Mat).
- Magazine article from: Science News Travis, J. April 12, 2003 700+ words
...signal that enables these primordial germ cells to hone in on the gonads. The discovery...mice, the chemical lure for primordial germ cells is a protein known as stromal cell...influences the movement of primordial germ cells, Nagasawa's team studied a mutant...
- Mouse embryonic germ cells and male gametes created in the lab.
- Newspaper article from: Drug Week January 2, 2004 700+ words
...continuously growing line of embryonic germ cells - primitive cells in the embryo that...edition of the journal Nature. Embryonic germ cells are a unique group of cells that the...days. Next, the researchers isolated germ cells from the embryoid bodies and cultured...
- Decisions, Decisions: Male or Female? How Germ Cells Decide Whether to Be Sperm...
- News wire article from: Ascribe Higher Education News Service August 26, 2005 700+ words
...developing embryos tell their specialized "germ cells" whether to develop into a male's...Present in both male and female embryos, germ cells are the precursors to both sperm and...their own which to become, however, germ cells must take "advice" from other cells...
- CIS/ITGCNU arises from developmentally arrested germ cells.
- Newspaper article from: Blood Weekly September 23, 2004 700+ words
...arises from developmentally arrested germ cells. "Several proteins, such as the placental...in both normal immature and malignant germ cells, known as carcinoma in situ/intratubular...with varying intensity was found in all germ cells, while TSPY was predominantly located...
