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Said to have 100% specificity, sensitivity: investigational ovarian Ca test proves accurate.(Gynecology)

OB GYN News

| April 15, 2004 | Bates, Betsy | COPYRIGHT 2004 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

UNIVERSAL CITY, CALIF. -- Researchers who reported in 2002 that they could identify ovarian cancer by viewing serum protein patterns with a mass spectrometer now say that with advanced techniques, the test is 100% accurate.

"A blood test exists today that can identify ovarian cancer with 100% sensitivity and specificity," Dr. David A. Fishman, director of the National Ovarian Cancer Early Detection Program, said at a meeting of the Obstetrical and Gynecological Assembly of Southern California.

The test is currently not ready to be incorporated into clinical practice as a screening tool, but variations on the technology may soon be available as part of a new, multipronged approach to early detection of ovarian cancer. It may have application to other diseases as well, including breast and prostate cancers, he said.

Dr. Fishman, in collaboration with Dr. Lance Liotta of the National Cancer Institute and Dr. Emanuel Petricoin of the Food and Drug Administration used high-resolution mass spectrometry to refine the proteomic pattern analysis that was hailed as a potential breakthrough in the detection of ovarian cancer when their first study was published (Lancet ...

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