AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Morbidity, mortality still high in patients with APS.(Clinical Rounds)
SAN DIEGO -- Morbidity and mortality remain high in patients with antiphos-pholipid syndrome despite current therapy with anticoagulants and low-dose aspirin, Dr. Ricard Cervera reported in a late-breaking poster session at the annual meeting of the American College of Rheumatology.
This observation has emerged from the ongoing Euro-Phospholipid Project, which began in 1999 and includes 1,000 patients from 13 European countries. The mean age of the patients is 47 years, and 82% are female. On enrollment, all met proposed preliminary criteria for the classification of definite antiphospholipid syndrome (APS).
During 5 years of follow-up, 20% of patients have had a thrombotic event. Among patients with thrombotic events were 24 who presented with strokes, 24 with transient ischemic attacks, 21 with deep vein thrombosis, 21 with pulmonary embolism, and 17 with skin ulcers.
Additionally, five patients developed catastrophic APS, according to Dr. Cervera of the Hospital Clinic, Barcelona.
The main APS therapies being used were oral anticoagulants, which were taken by 42% of patients, and low-dose aspirin, which was used by 35%. At the time of the thrombotic event, 121 patients were ...
- Genetic susceptibility to VTE: a primary care approach. after treatment of an...
- Magazine article from: JAAPA-Journal of the American Academy of Physicians Assistants Ridings, Herbert D. Holt, Lynn Cook, Rebecca Marques, Marisa B. July 1, 2009 700+ words
...disorders * Explain the treatment of patients with thrombophilic disorders Approximately...conditions as well as determine which patients should be referred to a hematologist...of testing, and the follow-up for patients who test positive for one or more of...
- Extreme Thrombocytosis in Trauma Patients: Are Antiplatelet Agents the Answer?
- Magazine article from: The American Surgeon Saadi, Zainab; Inaba, Kenji; Barmparas, Galinos; Salim, Ali; Talving, Peep; Plurad, David; Green, Donald; Demetriades, Demetrios October 1, 2009 700+ words
...cent in trauma patients. Antiplatelet...not affect ExT patient outcome. Further...count in every patient. Encountering...high values in patients who do not have...may develop a thrombotic event.5, 8~10 Many...
- HIT (Heparin-Induced Thrombocytopenia) Complications in Cancer Patients.
- Newspaper article from: Clinical Oncology Alert August 1, 2004 700+ words
...month period, 64 patients met the above criteria...in the other 44. The patients with malignancy all...organs, except one patient with melanoma. Thrombotic...more frequently in the patients with malignancy when...some form of adverse thrombotic event in 73% (8 of 11...
- New Data from 20 Studies with More Than 17,000 Patients Showed a 62 Percent...
- Press release article from: Business Wire October 25, 2002 700+ words
...studies with a total of 2,142 elderly patients (mean age 75; VIOXX n=1,067...approximately 14 months. The number of patients with a serious cardiovascular thrombotic event was 21 for patients treated with VIOXX 25 mg once daily...
- La Jolla Pharmaceutical Announces Results of Phase I/II Trial In...
- Press release article from: PR Newswire October 27, 2002 700+ words
...GP1in a majority of patients. Additional analyses...consisting of four or five patients, were treated with...monitored for 30 days. One patient in each group received...participate in the trial, patients were required to have...experience their first thrombotic event in their 20s or ...
- Regeneron and Bayer HealthCare Announce VEGF Trap-Eye Achieved Durable...
- Press release article from: Business Wire August 19, 2008 700+ words
...from the 52-week study. Patients receiving four monthly doses...subsequent PRN dosing phase, patients initially dosed on a 2.0...week 52 PRN dosing period, patients from all dose groups combined...study eye and one arterial thrombotic event, neither of which was deemed...
- Researchers from University of Padua detail new studies and findings in the...
- Newspaper article from: Blood Weekly April 2, 2009 700+ words
...collected at enrolment and at the time of the thrombotic event. 370 patients/subjects (mean (SD) age 34 (9.9) years...Thirty patients (8.1%) developed a first thrombotic event during follow-up. Hypertension and medium...
- From ice to Surgicel, tips to help control Mohs bleeding.(CUTANEOUS ONCOLOGY)
- Magazine article from: Skin & Allergy News McNamara, Damian June 1, 2009 700+ words
...the risk of a thrombotic event is much worse for the patient than the risk...recommended that patients with a history...ischemic attack or thrombotic event, in particular...therapy. Ask patients to provide...avoid placing a patient in the Trendelenburg...
Source: HighBeam Research, Morbidity, mortality still high in patients with APS.(Clinical Rounds)