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Many at-risk women aren't opting for tamoxifen.(Gynecology)
SAN ANTONIO -- Lifestyle approaches to breast cancer risk reduction have assumed considerable importance for the many women who have turned a cold shoulder to tamoxifen for chemoprevention, according to Leslie Bernstein, Ph.D., professor of preventive medicine at the University of California, Los Angeles.
"In my discussions with colleagues, word of mouth is that women are not flocking to take tamoxifen to reduce their high risk of breast cancer," she observed at a breast cancer symposium sponsored by the Cancer Therapy and Research Center.
This anecdotal impression is borne out by the recent literature. In three of four studies of tamoxifen's acceptance for prevention of breast cancer by high-risk women after counseling about the extent of their risk and the pluses and minuses of tamoxifen, only 3%-15% of candidates opted for therapy, although in another study the rate was 42%.
A recent report by Debora A. Paterniti, Ph.D., and coworkers at the University of California, Davis, Center for Health Services Research in Primary Care provides insight into why so many eligible women are unwilling to take ...
- Tamoxifen as a breast cancer preventive - many questions remain.
- Newspaper article from: HealthFacts Napoli, Maryann May 1, 1998 700+ words
...five deaths in the tamoxifen group (three from breast cancer, two from pulmonary...placebo group (all from breast cancer). The tamoxifen study, known as the...what their risk of breast cancer. Tamoxifen's most serious complications...
- Tamoxifen Cuts Risk of Contralateral Breast Cancer.
- Magazine article from: OB GYN News ZOLER, MITCHEL L. March 1, 2001 700+ words
...standard duration of tamoxifen therapy for preventing breast cancer is 5 years; when...for contralateral breast cancer associated with tamoxifen use. The results...for women without breast cancer. "I would offer tamoxifen at age 25 to offer...
- Tamoxifen and Breast Cancer Incidence Among Women with Inherited Mutations in...
- Magazine article from: OB/GYN Clinical Alert January 1, 2002 700+ words
Tamoxifen and Breast Cancer Incidence Among Women with...mutations who developed breast cancer, 5 received tamoxifen and 3 got placebo. King...mutations who developed breast cancer, 3 got tamoxifen and 8 received placebo...
- The Breast Cancer Prevention Trial: new finding on tamoxifen.
- Newspaper article from: HealthFacts April 1, 1994 700+ words
...reported deaths among tamoxifen-treated breast cancer patients taking part...affect the use of tamoxifen by women with breast cancer. Because the drug...seen in women with breast cancer not treated with tamoxifen, and this figure...
- Update on Tamoxifen- Associated Endometrial Cancer in Breast Cancer Patients.
- Magazine article from: OB/GYN Clinical Alert January 1, 2000 700+ words
...Feature Update on Tamoxifen- Associated Endometrial Cancer in Breast Cancer Patients By David...associated with tamoxifen therapy for breast cancer (OR = 1.52...487 women with breast cancer, 357 treated with tamoxifen and 130 controls...
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- Newspaper article from: Women's Health Letter Fuchs, Nan Kathryn April 1, 2001 700+ words
...a poor prognosis. Tamoxifen to prevent breast cancer A study using tamoxifen...women who developed breast cancer after taking tamoxifen would have tumors...between using 20 mg of tamoxifen to prevent breast cancer and using a placebo...
- New hope for women at risk.(tamoxifen may reduce breast cancer risk for some...
- Magazine article from: Newsweek Begley, Sharon April 20, 1998 700+ words
...in the trial, tamoxifen reduced the incidence of breast cancer a full 45 percent...incidence of invasive breast cancer among women receiving tamoxifen--85 cases compared...did 85 women on tamoxifen still get breast cancer (and, in three...
- Breast cancer drug to be approved for the healthy but high risk. (tamoxifen)
- Newspaper article from: HealthFacts October 1, 1998 700+ words
...recommend approval of the breast cancer drug, tamoxifen, for the "short-term...lower incidence of breast cancer in the tamoxifen-treated women represents...difference in the rate of breast cancer in tamoxifen-treated women, as...
Source: HighBeam Research, Many at-risk women aren't opting for tamoxifen.(Gynecology)