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As the new year begins, supplements for weight loss are being advertised everywhere (and this magazine is no exception). One of these supplements is CLA, or conjugated linoleic acid. Recently published studies have shed some light on how this fat-loss aid may work.
"We have identified a specific isomer (trans-10, cis-12) of CLA that causes mature human fat cells to lose their fat and become smaller," explains Michael McIntosh, PhD, RD, of the University of North Carolina-Greensboro, who headed the study (published in the September 9, 2005 issue of the Journal of Biological Sciences). Unfortunately, the study also found that this isomer prevents human fat cells from taking up glucose and fatty acids, which could increase blood sugar and lipids and as a result increase the risk of diabetes and cardiovascular disease. More research is needed on the trans-10, cis-12 CLA isomer of CLA in humans and potential side effects.
But other CIA studies using a mixture of CLA isomers ...