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Change in color can be earliest sign of melanoma.(Clinical Rounds)

OB GYN News

| December 01, 2005 | Kirn, Timothy F. | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

VANCOUVER, B.C. -- Color change, in addition to color variegation, often heralds melanoma, thus bolstering the need for adding an E to the ABCD mnemonic for melanoma detection, Robert J. Friedman, M.D., said at the Sixth World Congress on Melanoma.

The color change appears to occur often before a melanoma exhibits a change in diameter, meaning it can signal a melanoma long before its diameter reaches 6 mm, said Dr. Friedman, an originator of the ABCD criteria.

Dr. Friedman said he followed 24 very small lesions (2.3-5.7 mm in diameter) that, when removed after a period of observation, were found to be melanomas.

In 17 of the 24 lesions, color was the first change noted, followed by a change in diameter, then the appearance of asymmetry.

Only two lesions were invasive; both had a diameter greater than 4 mm. This is consistent with ...

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Source: HighBeam Research, Change in color can be earliest sign of melanoma.(Clinical Rounds)

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