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Very early pregnancy data favor myomectomy.(Gynecology)

OB GYN News

| November 15, 2005 | MacNeil, Jane Salodof | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

NICE, FRANCE -- Preliminary results from a prospective randomized trial in the Czech Republic show more women of reproductive age becoming pregnant after myomectomy than after uterine fibroid embolization.

Ten pregnancies were reported among 18 women who tried to conceive after uterine fibroid embolization (UFE). Twenty pregnancies occurred among 30 patients who sought to become pregnant after myomectomy.

So far, two babies have been born to mothers who had embolization, and 10 babies have been born to mothers who underwent myomectomy.

The investigators have declined to draw conclusions on outcomes at this point, however, because the number of women attempting pregnancy after embolization was relatively small.

"In terms of fertility, these are preliminary results. We draw no conclusion at the moment in terms of outcomes," investigator Michal Mara, M.D., Ph.D., told this newspaper after she presented data at the annual meeting of the Cardiovascular and Interventional Radiological Society of Europe.

"I think in the group with UFE, there were fewer patients trying to conceive at the moment. It was too small," he said, adopting a watch-and-wait approach for the ongoing study.

The trial randomized 49 women to embolization and 56 to myomectomy (33 laparoscopic procedures and 23 open myomectomies were performed).

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