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Endothelial dysfunction remains 1 year after preeclamptic pregnancy.(Obstetrics)

OB GYN News

| November 01, 2005 | Jancin, Bruce | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

STOCKHOLM -- Marked maternal endothelial dysfunction remains present a full year after a preeclamptic pregnancy, Maria J. Eriksson, M.D., Ph.D., reported at the annual congress of the European Society of Cardiology.

One year post partum, women with a history of preeclampsia have significantly higher blood pressure and fasting insulin and blood glucose levels than healthy controls who had a normal pregnancy. These physiologic and metabolic abnormalities help explain the association between preeclampsia and increased risk of cardio-vascular disease, said Dr. Eriksson of Karolinska University, Stockholm.

She presented a 1-year follow-up on 18 women who had moderate to severe preeclampsia in their first pregnancy and 17 age-matched controls with an uncomplicated pregnancy.

Brachial artery flow-mediated vasodilation as assessed by ultrasound--a standard noninvasive tool for the identification of endothelial dysfunction--was 2.5% in women with a history of preeclampsia, compared with 10.3% in controls. Flow-mediated dilation measured 1 year post ...

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Source: HighBeam Research, Endothelial dysfunction remains 1 year after preeclamptic...

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