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Vesicare.(drug approval)

Publication: Internal Medicine News

Publication Date: 15-DEC-04

Author: Mechcatie, Elizabeth
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COPYRIGHT 2004 International Medical News Group

Vesicare

(solifenacin succinate, Yamanouchi Pharmaceutical Co.)

A muscarinic receptor antagonist for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

* Recommended Dosage: 5 mg once a day; if well tolerated, can be increased to 10 mg once a day. No more than 5 mg daily for patients with renal or moderate hepatic impairment, and those taking CYP3A4 inhibitors, such as ketoconazole. Not recommended for patients with severe hepatic...

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