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Gene Mutations Affect Inhalant Response.(human response to inhaled endotoxin)(Brief Article)

Publication: USA Today (Magazine)

Publication Date: 01-JUN-01
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COPYRIGHT 2001 Society for the Advancement of Education

Researchers at the University of Iowa, Iowa City, have found the first genetic evidence that mutations to a certain gene are associated with differences in the human response to inhaled endotoxin, a contaminant commonly found in agricultural dust, air pollution, and household dust. They determined that mutations in the toll-like receptor-4 (TLR4) gene can cause some people to be less responsive to inhaled endotoxin and less prone to develop an asthma-like reaction when exposed...

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