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PHILADELPHIA -- Women who reported a history of infertility had higher rates of ectopic pregnancies, miscarriages, and stillbirths, according to a new analysis of data from the Women's Health Initiative.
The findings suggest that women who take longer than 1 year to conceive, despite not using contraception, should be monitored carefully in early pregnancy, Rahi Victory, M.D., said at the annual meeting of the American Society for Reproductive Medicine.
Previous studies have suggested that a history of infertility is associated with adverse obstetrical outcomes; however, these studies have been limited by small numbers, methodologic flaws, and a failure to control for confounding factors, said Dr. Victory, a second-year fellow in the reproductive endocrinology and infertility program at Wayne State University in Detroit.
Dr. Victory and his associates analyzed entry questionnaires from almost 162,000 participants in the Women's Health Initiative. Slightly more than 26,000 of these women reported a history of infertility, defined as taking more than 1 year to conceive. After controlling for multiple ...