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MgS[O.sub.4] does not raise disability risk in children: follow-up study of Magpie Trial participants also shows no increased risk of death.(News)
VIENNA -- The use of magnesium sulfate for the treatment of preeclampsia does not appear to increase the long-term risk of death or neurosensory disability in children. Lelia Duley, M.D., reported at the 14th World Congress of the International Society for the Study of Hypertension in Pregnancy.
The findings come from a follow-up study of subjects who participated in the landmark multinational Magpie (Magnesium Sulfate for Prevention of Eclampsia) Trial, in which 10,141 pregnant women with preeclampsia--from the developed and the developing world--were randomized to receive magnesium sulfate (MgS[O.sub.4]) or placebo. Women who received MgS[O.sub.4] had a 58% lower risk of eclampsia and a 45% lower risk of death, with no clear difference in the risk of death among the newborns up until the time of hospital discharge (Lancet 2002;359:1877-90).
Now, an 18-month follow-up among 4,782 women and 4,483 children from the original trial suggests that in utero exposure to the drug is not associated with long-lasting damage. "It's very reassuring," said Dr. Duley an obstetric epidemiologist at the Resource Center for Randomized Trials, Institute of Health Sciences, Oxford, England.
A total of 13.9% of the children of the mothers who received MgS[O.sub.4] before delivery had died by the time of follow-up, not ...
- Exposure to MgS[O.sub.4] appears not to raise offspring's risk.(Women's Health)
- Magazine article from: Family Practice News March 15, 2005 700+ words
...to receive magnesium sulfate (MgS[O.sub.4]) or placebo. Women who received MgS[O.sub.4] had a 58% lower risk of...children of the mothers who received MgS[O.sub.4] before delivery had died...
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...offers several advantages over MgS[O.sub.4], including its lack of lifethreatening side effects (MgS[O.sub.4] is a respiratory and cardiac...with minimal need for monitoring; MgS[O.sub.4] is given parenterally. In...
- No cognitive deficits in preeclamptics on MgS[O.sub.4].(Obstetrics)
- Magazine article from: OB GYN News Tucker, Miriam E. January 15, 2005 700+ words
...treated with magnesium sulfate (MgS[O.sub.4]) for preeclampsia appear...preeclampsia who were treated with MgS[O.sub.4], 15 women in preterm labor who received tocolytic MgS[O.sub.4], and 15 normal laboring...
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...compared 78 women who received MgS[O.sub.4] tocolysis for longer than 48 hours with 77 women who received MgS[O.sub.4] tocolysis for 48 hours or...who had received large amounts of MgS[O.sub.4] showed radiolucent bones...
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- Magazine article from: Solutions - for People, Processes and Paper Li, Zhiqing Ni, Yonghao van Heiningen, Adriaan R.P. December 1, 2001 700+ words
Application: This research suggests an effective method to remove manganese from pulp fibers. Removal of manganese from pulp fibers is usually achieved in a chelation stage with DTPA or EDTA. It can also be carried out in a treatment with magnesium sulfate via the so-called ion exchange technique.
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- Magazine article from: Business Times (Malaysia) March 4, 2002 700+ words
...The government papers include MGS, Treasury bills, government...position to an upward shift of the MGS benchmark yield curve. "I view...facilities at 40 per cent with a sub-limit for unsecured facilities...investing guidelines for insurers. MGS' strengths are their wide range...
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- News wire article from: Asia Africa Intelligence Wire December 3, 2004 700+ words
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- Newspaper article from: Defense Daily August 22, 2008 700+ words
...326.5 million to produce Stryker Mobile Gun System (MGS) variant vehicles. The contract, issued by Army TACOM...has initial funding of $145 million for 62 Stryker MGS. The Stryker MGS is one of 10 Stryker variants fielding to the Army in...
Source: HighBeam Research, MgS[O.sub.4] does not raise disability risk in children: follow-up...