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Antenatal hepatitis B screening program effective in Italian women.

Vaccine Weekly

| April 16, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 APR 16 - (NewsRx.com & NewsRx.net) -- Italy's antenatal hepatitis B screening program is effective in preventing perinatal transmission of the disease, an epidemiologic study found.

T. Stroffolini and colleagues evaluated the program's effectiveness in preventing perinatal HBV transmission "in 11,858 pregnant women consecutively recruited in public and private hospitals in six Italian regions during a two month period in 2001. Of [these women], 10,881 (91.8%) attended HBsAg antenatal screening."

The researchers reported the overall HBsAg prevalence as 1.7% (CI 95%: 1.4-1.9). By group, prevalence was 1.4% (CI 95%: 1.2-1.7) in pregnant women born in Italy, but 5.9% (CI 95%: 4.1-8.1) in those born in Asia, Africa, central and south America, and eastern Europe."

Statistical analysis indicated that birthplace outside of Italy, having more than four members living in the household, and birth in a private hospital were independent predictors of lack of adherence to HBsAg screening, Stroffolini's group said.

"Out of the 182 newborns of HBsAg positive mothers, 172 (95.0%) were given active plus passive immunization; this figure was 100% in newborns of foreign mothers," the researchers reported.

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Source: HighBeam Research, Antenatal hepatitis B screening program effective in Italian women.

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