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Doppler waveform analysis is useful in diagnosing cervical lymphadenopathy.

Women's Health Weekly

| April 10, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 APR 10 - (NewsRx.com & NewsRx.net) -- Doppler waveform analysis is useful in diagnosing cervical lymphadenopathy.

According to a study from Croatia, "We compared Doppler spectral parameters in acute inflammatory, reactive, lymphomatous, and metastatic lymph nodes, and evaluated pulsed Doppler sonography as a method for distinguishing between different causes of cervical lymphadenopathy."

"Spectral Doppler analysis with measurements of resistance index (RI), pulsatility index (PI), peak systolic velocity (PSV), and end-diastolic velocity (EDV) was performed in 197 patients with cervical lymphadenopathy. Results of Doppler analysis were compared with findings of cytology and histology or with clinical presentation and follow-up" stated Z. Brnic and coauthors, University of Zagreb, Hospital Merkur.

"Student's t-test was used to assess statistical significance of differences in Doppler parameters between groups of patients. Significant differences for RI and PI were shown between all groups of patients except between lymphomatous and reactive nodes. Specificity of 100% for metastatic nodal involvement was shown for cutoff values RI > 0.80 and PI > 1.80," the researchers stated.

"A positive predictive value (PPV) of 100% for acute lymphadenitis was shown for cutoff values RI <0.60. An EDV> 9 cm/s has 100% negative predictive value for nodal metastasis, and EDV

Brnic and coauthors concluded: ...

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