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2003 APR 10 - (NewsRx.com & NewsRx.net) -- Doppler waveform analysis is useful in diagnosing cervical lymphadenopathy.
According to a study from Croatia, "We compared Doppler spectral parameters in acute inflammatory, reactive, lymphomatous, and metastatic lymph nodes, and evaluated pulsed Doppler sonography as a method for distinguishing between different causes of cervical lymphadenopathy."
"Spectral Doppler analysis with measurements of resistance index (RI), pulsatility index (PI), peak systolic velocity (PSV), and end-diastolic velocity (EDV) was performed in 197 patients with cervical lymphadenopathy. Results of Doppler analysis were compared with findings of cytology and histology or with clinical presentation and follow-up" stated Z. Brnic and coauthors, University of Zagreb, Hospital Merkur.
"Student's t-test was used to assess statistical significance of differences in Doppler parameters between groups of patients. Significant differences for RI and PI were shown between all groups of patients except between lymphomatous and reactive nodes. Specificity of 100% for metastatic nodal involvement was shown for cutoff values RI > 0.80 and PI > 1.80," the researchers stated.
"A positive predictive value (PPV) of 100% for acute lymphadenitis was shown for cutoff values RI <0.60. An EDV> 9 cm/s has 100% negative predictive value for nodal metastasis, and EDV
Brnic and coauthors concluded: ...
Source: HighBeam Research, Doppler waveform analysis is useful in diagnosing cervical...