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Researchers propose a parametric model for long-term follow-up.(breast cancer)(Brief Article)

Women's Health Weekly

| April 10, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 APR 10 - (NewsRx.com & NewsRx.net) -- Researchers propose a parametric model for long-term follow-up.

According to recent research from the United States, "We propose a parametric version of a univariate gamma frailty model."

"The proposed model is shown to be flexible enough to model long-term follow-up survival data from breast cancer clinical trials when the treatment effect diminishes as time progresses, a case for which neither the proportional hazards nor proportional odds assumptions are satisfied," wrote J.H. Jeong and colleagues, University of Pittsburgh, Department of Biostatistics.

"The observed information matrix is computed to evaluate the variances of parameter estimates. A simple parametric test statistic to test proportional odds assumption is also constructed. The model is ...

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