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Exaggerated regulatory factors boost vascularization in women with adenomyosis.(endometriosis)
2003 APR 10 - (NewsRx.com & NewsRx.net) -- Exaggerated regulatory factors boost vascularization in women with adenomyosis.
"In adenomyosis, the two major frequent symptoms are hypermenorrhea and dysmenorrhea. The incidence of the former is said to be high, ranging from 36% to 70%. It has been found that vascular distribution of the endometrium in adenomyosis is diversely different from fertile patients without adenomyosis," researchers in Japan report.
"For example, hysteroscopy revealed that approximately half of the patients have abnormal vascularization. In these patients, vascular distribution was generally irregular, and vessels were thick, dilated, and/or reticular in some patients," wrote H. Ota and colleagues, Akita University, School of Medicine.
"Moreover, morphometric analysis of the endometrium revealed that in the fertile women, the mean surface area, total surface area, and total number of capillaries, all increased significantly in the secretory phase compared to the proliferative phase. In contrast, the above parameters increased in the adenomyosis group in both the proliferatve phase and secretory phase compared to the fertile women," researchers reported.
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