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Postmenopausal women with heart disease benefit from exercise regardless of HRT status.(hormone replacement therapy)
2003 APR 10 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Postmenopausal women with cardiovascular disease who undergo a training regimen reap benefits regardless of whether they are on hormone replacement therapy, researchers in Canada report.
Lori D. Kirwan and collaborators at the University of Toronto conducted a study involving 38 postmenopausal women to determine whether hormone replacement therapy influences the central and peripheral cardiovascular effects of an exercise program. Eighteen of the women received hormone replacement therapy (HRT) and 20 did not receive hormone therapy (N-HRT).
The women walked at 75%-80% of baseline peak oxygen uptake (VO[subscript]2peak) for an hour 5 days/week for 26 weeks. The investigators measured VO[subscript]2peak, ventilatory anaerobic threshold (AT), submaximal cardiac output (Q), and resting and peak ischemic blood flows (BF) at baseline, and 12 and 26 weeks.
"The HRT group was significantly younger than the N-HRT group and had significantly higher VO[subscript]2peak at baseline, yet either did not influence changes in other variables," reported the researchers.
Overall, VO[subscript]2peak increased by 5% over baseline in all of the women at 12 weeks and by 15% at 26 weeks (p
"The cardiovascular responses to training in postmenopausal women with CAD appear to be consistent regardless of HRT status and dominated by peripheral adaptations," concluded Kirwan and her coauthors (Exercise training in women with heart disease: Influence of hormone replacement therapy. Medicine and Science in Sports ...
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Source: HighBeam Research, Postmenopausal women with heart disease benefit from exercise...