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Morules with optically clear nuclei were found in an ovarian cancer.
2003 APR 3 - (NewsRx.com & NewsRx.net) -- Morules with optically clear nuclei were found in an ovarian cancer.
According to a study from Japan, "Optically clear nuclei (OCN) have been observed in morules of some neoplasms and in some conditions unrelated to the development of the morules. We first report a case of ovarian borderline endometrioid tumor (BET) showing the morules associated with OCN. The patient was a 47 year old premenopausal woman with a left ovarian cystic tumor, atypical endometrial hyperplasia, and elevated serum levels of FSH, LH, estradiol, and CA 125.
"The resected ovarian tumor measured 6 cm in diameter, and showed a papillary growth. Histologically, the ovarian tumor was consistent with BET, and the morules with OCN were scattered. Immunohistochemically, OCN were proven to be rich in biotin. An aberrant nuclear expression of beta-catenin was observed in both the tumor cells and the morular cells," stated C.H.C. Li and coauthors.
Li and coauthors concluded: "Our case may suggest the possibility that the appearance of OCN with or without morules in ovarian tumors is related to endometrioid differentiation of the tumor cells, and should be ...
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Source: HighBeam Research, Morules with optically clear nuclei were found in an ovarian cancer.