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Lactation decreases leptin secretion in rats.
2003 APR 3 - (NewsRx.com & NewsRx.net) -- Lactation decreases leptin secretion in rats, but the effect of leptin on the hyperphagia of lactation is not completely clear.
"The factors regulating serum leptin concentration and its relationship to the hyperphagia of lactation have been investigated in rats. Lactation results in hypoleptinemia and loss, or at least marked attenuation, of the nocturnal rise in serum leptin," researchers in Scotland report.
"Litter removal resulted in a fall in food intake and restoration of the nocturnal rise in serum leptin," said R. G. P. Denis and colleagues at the Hannah Research Institute. "Returning the litter to the mother after a 48-hour absence increased food intake and began to reinitiate milk production, but the nocturnal serum leptin levels were still increased at 48 hours after litter restoration. Adjusting litter size to four, eight, ten, or fourteen pups at parturition resulted in different rates of litter growth and food intake during the subsequent lactation, but had no effect on the degree of hypoleptinemia. Reducing litter size from ten to four pups at mid-lactation resulted in a transient increase in both serum leptin and pup growth rate, while food intake fell to a level found in rats suckling four pups throughout lactation. Reducing milk production by injection of bromocriptine increased serum leptin, but did not restore the nocturnal rise in serum leptin; food intake ...
- Serum leptin levels in rheumatoid arthritis and relationship with disease...
- Magazine article from: Southern Medical Journal Gunaydin, Rezzan Kaya, Taciser Atay, Aysenur Olmez, Nese Hur, Aysel Koseoglu, Mehmet October 1, 2006 700+ words
...Conclusions: Even though serum leptin levels were found to...correlation between serum leptin levels and TNF-[alpha...disease activity. However serum leptin levels positively correlated...weight by inhibiting food intake and stimulating energy...
- Increased serum leptin protects against adiposity.
- Newspaper article from: Biotech Week November 10, 2004 700+ words
...caused a reduction in food intake and decrease in body...The slightly increased serum leptin compensated for the...failed to decrease food intake or body weight in either...primary increase in serum leptin on the normal diet play...
- Low Serum Leptin In Non-Westernized Population Due To Lack Of Obesity.
- Newspaper article from: Obesity, Fitness & Wellness Week August 25, 2001 700+ words
...Saltmarsh, staff medical writer - Serum leptin levels in a given population can apparently...Journal of Internal Medicine compared serum leptin between non-westernized and westernized...population. Geometric mean titers of serum leptin in 163 Kitavan males and females were...
- Serum leptin is not a diagnostic marker for familial mediterranean fever...
- Magazine article from: Mediators of Inflammation Toy, Bulent Tarcin, Orhan Bagci, Sait Ustundag, Yucel Inal, Ali Tiftikci, Arzu January 1, 2006 700+ words
...Mediterranean fever (FMF) attacks and serum leptin levels. We enrolled 25 patients (22...investigated in the control subjects. The mean serum leptin levels before the attacks were 6.45...respectively. There was a slight increase in serum leptin levels during the attacks but it was...
- Serum copper levels positively associated with serum leptin concentrations.
- Newspaper article from: Obesity, Fitness & Wellness Week May 10, 2003 700+ words
...zinc, were positively associated with serum leptin concentrations in a healthy adult population...we investigated the association among serum leptin, zinc, copper, and zinc/copper...Biological Trace Element Research report. "Serum leptin assay was done with a commercial enzyme...
- Serum leptin levels decrease during prolonged high altitude exposure.
- Newspaper article from: Health & Medicine Week September 27, 2004 700+ words
...NewsRx.com & NewsRx.net) -- Serum leptin levels decrease during prolonged high...days at 5,050 m). Blood samples for serum leptin, plasma insulin and 24-hour urinary...altitude induces a decrease in fasting serum leptin concentrations in men," reported Zaccaria...
- High serum leptin levels could help manage asthma exacerbations.
- Newspaper article from: Immunotherapy Weekly April 2, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Serum leptin levels may play an important role in...colleagues from Istanbul University, studied serum leptin levels in 62 children with asthma before...were also studied as control subjects. Serum leptin levels were significantly higher in...
- Normal serum leptin activity found in obese patients.
- Newspaper article from: Obesity, Fitness & Wellness Week May 10, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Serum leptin activity was normal in obese patients...before." "In the present study, serum leptin activity was measured by an in vitro...their research in Regulatory Peptides (Serum leptin activity in obese and lean patients...