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C-reactive protein levels predict mortality risk.(in women with HIV)(Brief Article)

Women's Health Weekly

| April 03, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 APR 3 - (NewsRx.com & NewsRx.net) -- C-reactive protein (CRP) levels can predict the mortality risk for women infected with HIV.

CRP's link to mortality "was assessed in 209 HIV-1-infected women after adjusting for age, body mass index (BMI), serum albumin, CD4 cell lymphocyte count, and HIV-1 RNA" in a recent research from the United States.

"During the follow-up period of up to five years (median = 45 months) there were 49 deaths," according to J. G. Feldman and coauthors at the State University of New York Downstate Medical Center. "CRP at study enrollment was measured using a low sensitivity assay."

"CRP levels were only weakly correlated (Pearson correlation coefficient r

"The relative hazard associated with an elevated CRP level, independent of the covariates noted above, varied from 3.4- to 13.6-fold depending on how CRP values were grouped," study results showed.

The researchers concluded that "CRP may be a useful and inexpensive predictor of HIV disease mortality in women."

Feldman ...

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