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Local recurrence before 2 years following surgery predicts the worst outcome.(breast cancer recurrence)
2003 APR 3 - (NewsRx.com & NewsRx.net) -- Local recurrence before 2 years following surgery predicts the worst outcome.
According to a study from England, "Local recurrence of cancer in the treated breast following breast conserving surgery and radiotherapy occurs in a minority of patients, but can represent a significant clinical problem. The impact of local relapse on the subsequent course of the disease is disputed. The aim of this retrospective review was to identify the rate and prognostic factors for breast recurrence and to determine the subsequent outcome.
"The case notes of 2159 patients treated between 1989 and 1992 were reviewed. Actuarial local relapse rate was 6.3% at 5 years. Factors predictive for recurrence on multivariate analysis were age (p
McBain and coauthors concluded: "The prognosis of patients who developed recurrence within 2 years of their initial treatment was inferior to those who developed recurrences after 4 years (cancer-specific survival 5 years postrecurrence 23 vs. 57%, p=0.008). Systemic therapy should be considered for patients with early breast recurrence in view of their inferior survival."
McBain and colleagues published the results of their study in Clinical Oncology (Local recurrence of breast cancer following surgery and radiotherapy: incidence and outcome. Clin Oncol-uk, 2003;15(1):25-31).
The corresponding author for this report is ...
- Local recurrence before 2 years following surgery predicts the worst outcome.
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Source: HighBeam Research, Local recurrence before 2 years following surgery predicts the worst...