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Once weekly risedronate increases bone mineral density in postmenopausal women.
2003 APR 3 - (NewsRx.com & NewsRx.net) -- Once weekly therapy with risedronate increased bone mineral density in postmenopausal women.
"Risedronate 5 mg daily is approved by the Food and Drug Administration to treat postmenopausal osteoporosis. Gastrointestinal (GI) symptoms are common with daily bisphosphonates, but recent studies show that once weekly treatment may be better tolerated." researchers in the United States report.
"Risedronate 30 mg is approved to treat Paget's disease of bone," said Miriam F. Delaney and collaborators at Brigham and Women's Hospital in Boston. "In this retrospective study, we assessed the GI tolerability of 30 mg of risedronate once weekly and evaluated the effect on bone mineral density (BMD) in a subset of women. Review of patients treated in our osteoporosis clinic identified 150 postmenopausal women with low BMD treated with 30 mg of risedronate once weekly, between February 1998 and March 2001. Baseline GI symptoms or previous intolerance of bisphosphonates was present in 32 patients. An additional antiresorptive treatment was continued with risedronate in 50% of these patients (estrogen, raloxifene, or calcitonin). Risedronate 30 mg was taken once weekly with vitamin D 400 in daily and 1200 mg of calcium daily. Patient age ranged from 46 to 86 years. Baseline and follow-up BMD data ...
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Source: HighBeam Research, Once weekly risedronate increases bone mineral density in...