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Strain-related responses to DNA delivery to somatic cells reviewed.
2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Researchers present an overview of the delivery of deoxyribonucleic acid (DNA) to somatic cells.
According to recent research from the United States, "There is great potential in successful delivery of genetic material to somatic cells of animals and humans, not only to treat genetic deficiencies, but also to provide more effective therapies and vaccines."
"Concerted effort has been mounted over the past decade to validate the concept of gene-based therapy," reported Denny Liggitt at the University of Washington in Seattle. "Delivery of genes in vitro via multiple methods has demonstrated the biologic usefulness of the basic concept. However, application of similar gene delivery strategies to whole animal systems has been more difficult."
"Much of the complexity associated with gene delivery involves encounters with host biological barriers, including innate and acquired host responses to exogenous DNA, as well as specifically encoded proteins," said Liggitt. "Delivery of genetic material to somatic cells in vivo is a multi-factorial event involving variables in formulation, route, and dose, and target species or strain. In vivo expression of these variables can result in conflicting findings with ...
- Analytical Instrument quantifies somatic cells in milk.(Advanced Instruments...
- Magazine article from: Product News Network January 11, 2005 700+ words
...Analyzer enables dairy labs to quantify somatic cells in unpasteurized milk and identify...throughput, Accurate Analyzer Quantifies Somatic Cells in Milk -- NORWOOD, MASSACHUSETTS...effective way for dairy labs to quantify somatic cells in unpasteurized milk and identify...
- CHINESE RESEARCHERS CREATE EMBRYOS FROM HUMAN SOMATIC CELLS.
- News wire article from: BERNAMA The Malaysian National News Agency January 6, 2000 700+ words
...technology to create embryos from human somatic cells that could grow into skin, cartilage...of diseases. The researchers used somatic cells taken from a patient of an unidentified...transplanted the nuclei of the human somatic cells into the egg cells, whose nuclei had...
- Celprogen Introduces Non-Viral Method to Reprogram Adult Somatic Cells...
- Newspaper article from: Virus Weekly January 27, 2009 700+ words
...successfully De-DIFFERENTIATED Human Somatic Cells (primary skin fibroblast, keratinocytes...matrix system for reprogramming adult somatic cells to iPCs in tissue culture. The adult somatic cells were De-differentiated (reprogrammed...
- Celprogen introduces non-viral method to reprogramme adult somatic cells...
- News wire article from: Chemical Business Newsbase January 12, 2009 700+ words
...successfully De-Differentiated Human Somatic Cells (primary skin fibroblast, keratinocytes...matrix system for reprogramming adult somatic cells to iPCs in tissue culture. The adult somatic cells were De-differentiated (reprogrammed...
- Celprogen Introduces Non-Viral Method to Reprogram Adult Somatic Cells...
- Press release article from: Business Wire January 12, 2009 700+ words
...successfully De-DIFFERENTIATED Human Somatic Cells (primary skin fibroblast, keratinocytes...matrix system for reprogramming adult somatic cells to iPCs in tissue culture. The adult somatic cells were De-differentiated (reprogrammed...
- Loss of tumor suppressor causes mitotic failure in human somatic cells.
- Newspaper article from: Biotech Week June 9, 2004 700+ words
...degradation and mitotic failure in human somatic cells. According to a study from the United...employing RNA interference in human somatic cells, we found that severe reduction of...degradation and mitotic failure in human somatic cells. Proc Nat Acad Sci USA, 2004;101...
- Chinese researchers report success in using cloning to create embryos from...
- Newspaper article from: Transplant News February 16, 2000 700+ words
...technology to create embryos from human somatic cells that could grow into skin, cartilage...center on genetic engineering, used somatic cells taken from a patient of an unidentified...transplanted the nuclei of the human somatic cells into the egg cells, whose nuclei had...
- Scientists preserve somatic cells for future cloning of tigers.
- News wire article from: PTI - The Press Trust of India Ltd. July 15, 2007 700+ words
Scientists preserve somatic cells for future cloning of tigers Beijing, Jul 15 (PTI) Amid China...tiger products, Chinese scientists have started preserving somatic cells of south China tiger, a species thought to be extinct in the...
- World's first buffalo cloned from somatic cells in good shape.
- News wire article from: Asia Africa Intelligence Wire March 19, 2005 700+ words
...Mar 19 (PTI) World's first water buffalo, cloned from somatic cells in south China's Guangxi Zhuang Autonomous Region, was...has another two buffaloes pregnant with babies cloned with somatic cells and they are expected to be born this year," he said...
- China clones world's first rabbit from somatic cells.
- News wire article from: PTI - The Press Trust of India Ltd. July 24, 2007 700+ words
China clones world's first rabbit from somatic cells Beijing, Jul 24 (PTI): China has cloned the world's first rabbit from the somatic cells of the animal, allowing faster reproduction of genetically modified rabbits for medical use, the...
Source: HighBeam Research, Strain-related responses to DNA delivery to somatic cells reviewed.