AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
2003 MAR 19 - (NewsRx.com & NewsRx.net) -- DNA immunization offers new opportunities in vaccine research.
"A novel class of vaccines, based on the immunization with 'naked' DNA, may hold the promise of protecting against human disease without the disadvantages associated with vaccines presently used, and may help to prevent infections which are not curable today," researchers in Germany report.
"Direct intramuscular or intradermal inoculation of plasmid DNA encoding sequences of viral proteins results in the synthesis of these proteins, causing humoral and/or cellular immune responses in the recipient," stated A. Henke at Friedrich-Schiller University. "Several advantages are associated with DNA immunization, e.g., cheap to produce, heat stability, amenable to genetic manipulation, mimic viral infection, and no risk of reversion to pathogenicity. Nevertheless, some concerns remain regarding their safety, e.g., the possible integration of plasmid DNA ...
Source: HighBeam Research, DNA immunization offers new opportunities in vaccine research.(Brief...