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Survivin is an apoptosis antagonist.(Brief Article)
2003 MAR 13 - (NewsRx.com & NewsRx.net) -- Survivin is an apoptosis antagonist.
According to recent research from Japan, "survivin, a protein that inhibits apoptosis, is expressed in a variety of tumor cells."
"We detected survivin-specific mRNA and protein in normal placental tissues, two human choriocarcinoma cell lines (JEG-3 and BeWo), and a trophoblastic cell line (tPA30-1) by reverse transcription-polymerase chain reaction (RT-PCR), Northern blotting, and Western blotting," described A. Shiozaki and colleagues, Toyama Med & Pharmaceutical University, Department Obstetrics & Gynecology.
"Immunohistochemically, survivin was localized to normal villous cytotrophoblasts, normal extravillous trophoblasts, cytotrophoblasts in hydatidiform mole, and choriocarcinoma cells."
"Antisense oligonucleotides for survivin dose-dependently induced apoptosis in two choriocarcinoma cell lines (JEG-3 and BeWo) and a trophoblastic ...
- Survivin is an apoptosis antagonist.
- Newspaper article from: Cancer Weekly March 11, 2003 700+ words
...and colleagues, Toyama Med & Pharmaceutical University, Department Obstetrics & Gynecology...contact S. Saito, Toyama Med & Pharmaceutical University, Department Obstetrics & Gynecology...
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...Immunol, 2004;61(2):133-143). For additional information, contact S. Saito, Toyama Med & Pharmaceutical University, Department Obstetrics & Gynecology, 2630 Sugitani, Sugitani, Toyama 9300194, Japan. The publisher...
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- Newspaper article from: Cancer Weekly October 19, 2004 700+ words
...HeLa cells. Chem Pharm Bull Tokyo, 2004;52(8):1015-1017). For additional information, contact T. Hayashi, Toyama Med & Pharmaceutical University, Faculty Pharmaceutical Science, 2630 Sugitani, Toyama 9300194, Japan. Publisher contact...
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...University Hospital. Modern Pathol, 2004;17(9):1141-1149). For additional information, contact K. Tsuneyama, Toyama Med & Pharmaceutical University, Faculty Med, Department Pathology, 2630 Sugitani, Toyama 9300194, Japan. The publisher...
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...balance in preeclampsia. J Reprod Immunol, 2003;59(2):161-173). For additional information, contact S. Saito, Toyama Med & Pharmaceutical University, Dept Obstetrics & Gynecology, 2630 Sugitani, Toyama 9300194, Japan. Publisher...
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- Newspaper article from: Health & Medicine Week October 6, 2003 700+ words
...Wiskott-Aldrich syndrome. Int J Hematol, 2003;78(1):40-44). For additional information, contact H. Kanegane, Toyama Med & Pharmaceutical University, Faculty Med, Dept Pediatrics, 2630 Sugitani, Toyama 9300194, Japan. The publisher...
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- Newspaper article from: Health & Medicine Week January 5, 2004 700+ words
...as a prognostic predictor. Oral Oncol, 2003;39(8):829-835). For additional information, contact K. Matsui, Toyama Med & Pharmaceutical University, Faculty Med, Department Pathology, 2630 Sugitani, Toyama 9300194, Japan. The publisher...