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Cancer vaccine one step closer.

Vaccine Weekly

| March 12, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Andreea Ioan-Facsinay from Leiden University Medical Center has attached proteins from tumor cells to antibodies. With these she treated immune cells from a mouse. These treated cells were used to make a vaccine, which was shown to be effective in animal experiments.

If the follow-up research is successful, vaccines against cancer will become available. However, that will take at least 10 more years.

Vaccines against cancer are being sought on various fronts. That is not simple, as unlike the agents that cause most other diseases, cancer cells originate from within the body. Therefore, the immune system either does not recognize them or recognizes them too late.

In principle, Ioan-Facsinay managed to solve this problem for some types of cancer. She successfully attached material from the tumor to antibodies. The immune cells from the mouse were then treated with this complex and injected back into the mouse. The vaccine was made from these reinjected cells induced an immune response against this cancer in animal experiments. Certain proteins in the surface of the immune cells, the ...

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Source: HighBeam Research, Cancer vaccine one step closer.

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