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Heat shock/chaperone protein may act as natural adjuvant.(Brief Article)
2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Heat shock/chaperone protein (HSCP)-peptide complexes can access the cross-priming pathways of antigen presenting cells (APCs), and the gp96-associated peptides can be re-presented on APC MHC class I molecules to elicit CD8+ T cell activation. This immunological circuit is thought to provide the functional basis for HSCP function in tumor immunity."
"Recent findings identifying a 'natural adjuvant' function for HSCPs suggest complementary, or perhaps alternative, mechanisms of HSCP-mediated tumor rejection," stated Julie C. Baker-LePain and collaborators at Duke University Medical Center.
Baker-LePain and colleagues published the results of their study in Current Opinion in ...
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Source: HighBeam Research, Heat shock/chaperone protein may act as natural adjuvant.(Brief...