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Travelers spread HIV-1 genetic variants.(Brief Article)

Vaccine Weekly

| March 05, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "HIV-1 comprises three groups, the main (M group), 0 (outlier) and N (non-M, non-O). The M group, divided into 11 subtypes, is responsible for the global HIV-1 pandemic. Recombination between M subtypes has resulted in the generation of multiple circulating recombinant forms (CRFs) consisting of mosaic lineages," researchers in Switzerland report.

"Most subtypes and CRFs are represented in Africa, whereas predominance of one or a few subtypes was reported initially elsewhere," reported Luc Perrin and colleagues at the University of Geneva. "This finding reflects the African origin of the epidemic. In western countries, where the B subtype is predominant, there is a steep increase in non B-subtypes and CRFs, while new recombinants emerge worldwide."

The researchers concluded, "Travelers contribute to the spread of HIV-1 genetic diversity worldwide, and in the developing world migration of ...

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Source: HighBeam Research, Travelers spread HIV-1 genetic variants.(Brief Article)

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