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Molecular studies of Escherichia coli based infections are needed.
2003 MAR 6 - (NewsRx.com & NewsRx.net) -- "Urinary tract infection (UTI) is one of the most frequently acquired bacterial infections and Escherichia coli accounts for as many as 90% of all UTIs seen among ambulatory populations," researchers in the United States report.
"Risk factors for UTIs include host behaviors, host characteristics and bacterial characteristics. Sexual activity and contraceptive method are the strongest determinant of a symptomatic UTI episode," according to L.X. Zhang and colleagues, University of Michigan, School of Public Health.
"The characteristics of cell receptors, anatomical differences and genetic predisposition in the host may be important determinants of increased risk for recurrent infections. Uropathogenic E. coli have special characteristics causing urovirulence. They most likely belong to phylogenic lineage B2," said researchers.
"They usually possess specific adhesins such as P, S or Dr to facilitate their colonization in the urinary tract, and toxins such as hemolysin and cytotoxic necrotizing factor 1 to provoke inflammatory response that possibly are responsible for the development of UTI symptoms."
"Interestingly, virulence genes in uropathogenic E. coli are often co-located on pathogenicity islands. Currently, however, none ...
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- Magazine article from: Women's Health Weekly January 15, 2009 700+ words
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