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Sperm DNA fragmentation higher among some couples with recurrent miscarriage.(Brief Article)
2003 MAR 6 - (NewsRx.com & NewsRx.net) -- Some couples who experience repeated pregnancy loss may be hosts to sperm DNA fragmentation, according to researchers in the United States.
"Previous studies have indicated that sperm quality may be related to unexplained recurrent pregnancy loss. This study evaluated the degree of sperm DNA fragmentation using the TUNEL assay on sperm from 24 couples with unexplained recurrent pregnancy loss (RPL) compared to sperm from 2 control groups: donors of known fertility and unscreened men from the general population," wrote D.T. Carrell and colleagues, University of Utah, School of Medicine.
"The percentage of sperm staining positive for DNA fragmentation was increased (p
"These data indicate that some RPL patients have a significant increase of sperm DNA fragmentation, which may be causative of pregnancy loss in some patients," Carrel and coauthors concluded (Sperm DNA fragmentation is increased in couples with ...
- Sperm DNA fragmentation higher among some couples with recurrent miscarriage.
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A COMMERCIAL test for evaluating sperm DNA integrity is underused, according to...determine if a man has significant damage to sperm DNA. This damage can be caused by medications...explained. At the same time, integrity of sperm DNA is emerging as an independent measure...
Source: HighBeam Research, Sperm DNA fragmentation higher among some couples with recurrent...