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Strontium ranelate prevents early postmenopausal bone loss.
2003 MAR 6 - (NewsRx.com & NewsRx.net) -- According to a study from Belgium, "early postmenopausal women (n = 160) were randomized to receive placebo or strontium ranelate (SR) 125 mg/day, 500 mg/day or 1 g/day for 2 years (40 participants per group). All participants received calcium 500 mg/day. The primary efficacy parameter was the percent variation in lumbar bone mineral density (BMD), measured using dual-energy X-ray absorptiometry."
"Secondary efficacy criteria included hip BMD and biochemical markers of bone turnover. At month 24, SR I g/day significantly increased lumbar BMD compared with placebo [mean (SD) +5.53% (5.12); p
"The annual increase for adjusted values was +0.66% compared with -0.5% with placebo, with an overall beneficial effect after 2 years of about 2.4% with SR 1 g/day relative to placebo. There were no other significant between-group differences in adjusted lumbar BMD."
"Femoral neck and total hip BMD were also significantly increased at month 24 with SR 1 g/day compared with placebo [mean (SD): +2.46% (4.78) and +3.21% (4.68), respectively; both p
"No effect on markers of bone resorption was observed. SR was as well tolerated as placebo. The minimum dose at which SR is effective in preventing bone loss in early postmenopausal non-osteoporotic women is therefore 1 g/day," researchers ...
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...and tends to reduce weight gain in early postmenopausal women. "The aim of this study...body composition, and bone mass in early postmenopausal women in a partly randomized comprehensive...and tends to reduce weight gain in early postmenopausal women: A Randomized controlled...
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- Press release article from: PR Newswire December 2, 1998 700+ words
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- Bone microarchitecture can deteriorate in 1 year in early postmenopausal...
- Magazine article from: Women's Health Weekly August 1, 2002 700+ words
...network inside bone - can deteriorate in just 1 year in early postmenopausal women. This is an important new finding as the loss...to protect the trabecular microarchitecture of bone in early postmenopausal women at 1 year and to increase BMD. Data were presented...
- SR PHARMA PLC - Acquisition(s).
- Press release article from: PR Newswire UK Disclose June 21, 2005 700+ words
SR PHARMA TO ACQUIRE ATUGEN Proposed acquisition and temporary suspension 21 June 2005 - London - SR Pharma plc ("SR Pharma" or "the Company") is pleased to announce that it has entered...
- SR consumption to increase 4.1%. (International Institute of Synthetic Rubber...
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World synthetic rubber (SR) consumption is expected to increase by 4.1% but will...after what experts agree has been a truly dreadful period for SR producers worldwide. World SR consumption fell to 9,027 metric tons in 1993 from 9,660...
