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Hormone therapy could help prevent preterm births.
2003 MAR 6 - (NewsRx.com & NewsRx.net) -- Injections of a progesterone-type hormone may be able to prevent more than a third of preterm births in women with a history of giving birth early, reported Paul J. Meis, MD, of Wake Forest University Baptist Medical Center, at the Annual Meeting of the Society for Maternal-Fetal Medicine in San Francisco.
"The evidence of this treatment's effectiveness was so dramatic, the research was stopped early," said Meis, the national principal investigator and a professor of obstetrics and gynecology at Wake Forest. "This drug is readily available and can be used by doctors to improve outcomes for mothers and babies."
In women who received weekly injections of the drug 17-alpha-hydroxprogesterone caproate, also known as 17P, the risk of preterm birth before the 37th week of pregnancy was reduced by 34%. The preterm birth risk prior to 32 weeks was reduced by 42%.
"This is the first well-documented demonstration of a successful treatment to reduce preterm births in women at risk," said Meis.
The study involved 463 women who had a history of giving birth before the 37th week of pregnancy. They were treated at 19 centers that are members of the Maternal Fetal Medicine Units Network of the National Institute of Child Health and Human Development at the National Institutes of Health. In North Carolina, the other participating center was ...
- Hormone therapy could help prevent preterm births.
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Source: HighBeam Research, Hormone therapy could help prevent preterm births.