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Tetanus toxoid enhances hepatitis B vaccine response.

Vaccine Weekly

| February 12, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 FEB 12 - (NewsRx.com & NewsRx.net) -- Scientists have learned that tetanus toxoid enhances the response to hepatitis B virus vaccine in previous nonresponders.

According to a study from Turkey, "in this prospective study, our aim was to test the effect of simultaneous administration of preS2 and S containing recombinant hepatitis B vaccine (S2SRHB) with tetanus toxoid (TT) to the individuals who did not respond after three doses of hepatitis B vaccine previously."

"There were three groups (healthy individuals, pregnant women, and hemodialysis patients), each was divided into two subgroups as groups A and B. Group A received S2SRHB + TT and group B received only S2SRHB," said E. Sonmez and coauthors, Kadir Has University, Faculty of Medicine.

"We found that in groups receiving both vaccines, both seroconversion rate and antibody titer level were significantly higher (P

Sonmez and colleagues published the results of their study in Vaccine ...

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